Research Fellow – DIAMA Project (0.3 FTE) 226 views

The London School of Hygiene & Tropical Medicine is a world-leading centre for research and postgraduate education in public and global health. Our mission is to improve health and health equity in the UK and worldwide; working in partnership to achieve excellence in public and global health research, education and translation of knowledge into policy and practice.

We are seeking to appoint a statistician for the DIAMA (Culture-free diagnosis and follow-up of multi-drug resistant tuberculosis patients) project. They will work collaboratively with an inter-disciplinary research team, led by principal investigator (PI) Prof Dissou Affolabi who is based in Benin. The project is a large EDCTP-funded grant, with collaborating partners including the National Mycobacterial Reference Laboratory in Benin, the Rwanda Biomedical Centre in Rwanda, the Institute of Tropical Medicine in Belgium, LSHTM, and the Special Program for Research and Training in Tropical Diseases at the World Health Organisation (WHO/TDR). TB patients are recruited to the study across a range of countries in Western and Central Africa.

The post-holder will support two main research studies as part of the 5-year (2016-2021) DIAMA project. Study 1 is on the diagnosis of MDR-TB: Three to four novel molecular tests will be compared to the “reference standard” of culture, and also to whole-genome-sequencing results, to obtain estimates of their sensitivity, specificity, and negative and positive percent agreement compared with the “reference standard” of TB culture. Study 2 is on the management of MDR-TB patients; it will be done among patients who were diagnosed with MDR-TB in Study 1. It will compare one molecular test against culture, for monthly TB patient monitoring throughout TB treatment, and will evaluate two molecular tests for whether their trajectory of response over 1-2 months of treatment is able to accurately predict TB treatment outcomes.

The post-holder will have experience in the analysis of data from epidemiological studies, ideally prior experience of working on studies of tuberculosis and an MSc in Medical Statistics. The role will involve leading and/or contributing to analyses of data from both DIAMA studies, and leading and/or contributing to writing up findings for publication. It would be an advantage for the post-holder to speak French as well as English.  

The post is funded at 0.3 FTE until 31 October 2020 initially. The salary will be on the Academic scale, Grade 6 scale at £40,011 per annum pro rata.  The post will be subject to the LSHTM terms and conditions of service.  Annual leave entitlement is 30 working days per year, pro rata for part time staff. In addition to this there are discretionary “Director’s Days”. Membership of the Pension Scheme is available.

Applications should be made online via our website at . Online applications will be accepted by the automated system until 10pm of the closing date. Any queries regarding the application process may be addressed to . 

The supporting statement section should set out how your qualifications, experience and training meet each of the selection criteria. Please provide one or more paragraphs addressing each criterion. The supporting statement is an essential part of the selection process and thus a failure to provide this information will mean that the application will not be considered. An answer to any of the criteria such as “Please see attached CV” will not be considered acceptable.

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